BDBM50029257 (3-((4-(2-isopropoxyphenyl)piperazin-1-yl)methyl)phenyl)(piperidin-1-yl)methanone::CHEMBL10085::RWJ-377796::mazapertine::{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone
SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1
InChI Key InChIKey=ZKZFPRUSWCYSGT-UHFFFAOYSA-N
Data 25 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50029257
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor of rat brain synaptosomal preparationsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:In vitro ability to displace serotonin 5-HT1A receptor binding to rat cerebral cortex in competition experiments against [3H]-8-(hydroxy)dipropyl ami...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Compound was evaluated for its binding affinity against 5-hydroxytryptamine 1A receptor from rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Compound was measured in vivo for its binding affinity at 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Affinity against the 5-hydroxytryptamine receptor 1A using [3H]WB-4101.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101More data for this Ligand-Target Pair